![]() The year 2022 also saw the creation and listing of over 2.5 million NFTs.Īre your BTC holdings flashing green? Check the Profit Calculator Over 370,000 new traders joined the platform, increasing the number of active traders by over 2.5 times and trading volume by 3.5 times from the previous year. Launched in June 2021, Binance NFT marketplace added over 600,000 weekly users over the course of 2022, according to Binance NFT 2022 Year in Review report. Users who trade at least one NFT on the platform during the promotional period, which extends up to 19 June, stand a chance to share a total of 80 Bitcoin NFTs as per the rewards structure. In order to boost Bitcoin NFT trading activity on its marketplace, Binance came up with a rewards program. ![]() With the addition of Bitcoin, Binance further elevated its stature as a multi-chain NFT marketplace, which currently supports NFTs from blockchains like Ethereum, BNB Chain and the recently added Polygon. Binance stated that it intends to add support for more collections in the days to come. You can now buy, deposit, withdraw and list NFTs from the #BTC network directly from your #Binance account □įind out more ➡️ /ZwYGaT2aUSīinance is the latest entrant to step into the world of Bitcoin NFTs after leading player Magic Eden launched a secondary marketplace for Ordinals in March.Īccording to the blog post, iconic NFTs like Bitcoin Punks and Bitcoin Frogs, which were extensively traded last month, were among the collections available on the Binance NFT marketplace. Alexandre Arnault, Tiffany’s executive vice president of product and communications, previewed the launch in April.The #Bitcoin Network is now supported on Marketplace! Most associate the storied jeweler with Audrey Hepburn in Breakfast at Tiffany’s, its iconic blue jewelry boxes, and its largely out-of-reach price tag.īut a debut NFT collection might be Tiffany’s latest move in its years-long rebranding effort to appeal to younger shoppers. The collection may seem like a strange move from one of the most prominent names in the luxury goods sector since its founding in the 1800s. 12 to redeem their NFTs, and the physical pendants won’t be ready until early next year-according to Chain, the crypto startup Tiffany’s has partnered with for the project. ![]() ![]() But only CryptoPunk holders can redeem the physical necklace through minting-the process of turning a digital file into a crypto collectible or digital asset recorded on the blockchain. The design is meant to resemble each CryptoPunk owner’s character from the famed avatar collection.Īnyone can purchase an NFTiff pass to hold as a collectible, as long as they use a wallet where they own the private keys. ![]() Tiffany’s artisan designers will customize each pendant sold using a combination of at least 30 diamonds and gemstones, the company said. The values of cryptocurrencies such as Bitcoin and Ethereum are also down big after hitting highs late last year. CryptoPunks, considered a leader in the market, was no exception, and its floor price sank over 50% that month, The Block reported. The announcement about the passes comes after many NFT collections took a massive loss in value following May’s crypto market crash. ![]()
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![]() ![]() ![]() This research endeavor has resulted in the blossoming of a new area of molecular diagnosis. Bekim Sadikovic (London Health Sciences Centre, Ontario), began exploring the possibility that neurodevelopmental disorders may have unique methylation profiles (epi-signatures) as many causative genes were involved with the epigenetic machinery (histone modification, DNA methylation, chromatin remodeling). The enhancers, named exonic enhancers (eExons) regulate two genes involved in limb development, DLX5 and DLX6, which are 900 kb proximal to DYNC1I1 and the identification of eExons added another level of complexity to genetics In collaboration with a group at UCSF, in 2012, novel enhancers embedded in an exon of one gene, DYNC1I1, in the SHFM1 region in chromosome 7q21 was identified. Schwartz’s group identified a complex, chromosomal rearrangement in 10q24 that results in a small tandem duplication in SHFM3 patients. With respect to birth defects, a project was undertaken to identify genes responsible for ectrodactyly (split-hand/split-foot, SHFM). The purpose of the Polyamigos is to explore avenues for treatment of SRS. Schwartz was instrumental in bringing together a group of researchers, with various backgrounds and an interest in polyamine biosynthesis, to form a group named the ‘Polyamigos’. This gene converts spermidine to spermine, and affected males have an abnormally high ratio of these polyamines in their white cells. Schwartz’s group identified mutations in the spermine synthase gene (SMS) which are associated with Snyder-Robinson syndrome. Linkage was achieved in 72 of the families and 36 XLID genes were cloned, many in collaboration with groups spread throughout the world. Roger Stevenson, a senior clinical geneticist at GGC. Over 700 families were enrolled in the project, in collaboration with Dr. For the former, his laboratory concentrated on identifying genes responsible for X-linked intellectual disabilities (XLID). Schwartz’s research interests focused on the causes of intellectual disabilities and birth defects. From 1985 until his retirement in May 2019, Dr. Schwartz is an Emeritus Senior Research Scientist of the Greenwood Genetic Center (Greenwood, SC) and Chair, Medical and Scientific Advisory Board of the Snyder-Robinson Foundation. It allows a determination of the risk of recurrence, the possibility of other comorbidity medical problems, the molecular and cellular nature of the pathobiology and hopefully potential therapeutic approaches.Īutism spectrum disorders Intellectual disability Molecular pathways Neurodevelopmental disorder Synaptic plasticity.Ĭopyright © 2014 Elsevier Ltd. Understanding the etiology of either ID or ASD is of utmost importance for families. Nonetheless, much valuable information has been gained by identifying candidate genes for ID or ASD. The causative factors (genes, epigenetic and environmental) are quite varied and likely interact so as to further complicate the assessment of an individual patient. Additionally, they can be found together in the same individual thereby complicating treatment. ![]() Combined, they affect between 3 and 5% of the population. Intellectual disability (ID) and autism spectrum disorder (ASD) are the most common developmental disorders present in humans. ![]() ![]() The 240-volt outlets are larger than 120-volt outlets, and they have rounded tops with three or four holes. If you have not already installed four-prong 240-volt outlets, do it as they will solve any safety or compatibility issues. The 4th prong adds a ground wire, thus providing additional safety against electric shock. Now, these old three-prong 240V outlets are replaced with four-prong outlets. The older 3-prong outlets were designed to have two live wires and one neutral wire. The following appliances need a 240-volt plug installed to operate: The 240-volt outlets are meant for large, motor-driven appliances that need more electricity to run effectively. You need to know exactly where you should place your appliances to ensure they function efficiently. ![]() Planning your electricity in your home is absolutely essential. For example, an oven connected a 120V wire will only produce 1/4 the heat it would produce if it had been connected to a 240-volt outlet. When You Need 240 Volt Outlets?Īlthough a number of your appliances, such as oven, dryer, and washing machine, may technically run on 120V, they need more than that voltage to run efficiently. Older homes and appliances have three-prong 240-volt outlets, but today’s modern outlets and appliances use a ground wire too, which means a modern 240-volt plug has four prongs. The 240-volt outlet has two 120-volt wires and a neutral wire to power a single electrical appliance. What is a 240-Volt Outlet?Ī standard electrical outlet has a 120-volt wire and a neutral wire that works together to deliver power using one phase of your electrical service. You need to have both the 120-volt and 240-volt outlets depending on your needs and appliances. Going for only 120-volt outlets throughout your home is not safe. A 249-volt outlet is the larger type, which has a room for 3 or 4 individual plugs of varying sizes. A 120-volt outlet is the one you use to plug in your phone charger or vacuum cleaner. You should be able to distinguish between a standard 120-volt outlet and a 240-volt outlet. ![]() ![]() That’s why you need to have the right outlets installed. And not every outlet in your home can handle high voltage (240-volt) current. Consider the electric current flowing through the electrical wires in your home as pressure – the harder and quicker the electrons are pushed through the wires, the more power they will provide to the outlet. ![]() ![]() ![]() Anna did not always take kindly to Assing’s presence, as her relationship with Douglass was likely intimate as well as intellectual.Īssing’s biographer suggests that eventually, the two women reached some form of truce, but always held each other in contempt. ![]() During these visits, she consistently attempted to reshape Douglass’s thoughts on specific issues, helped with his newspaper, and worked on her own writing. For many Summers between the late 1850s and 1872, Ottilie became a frequent visitor to the Douglass household, serving as both Douglass’s intellectual and emotional companion. To expand the historical narrative beyond Douglass’s personal accounts, Blight decided to pull back the curtains, and his alternative narrative includes the experiences of Anna and Ottilie during the Civil War, which counters Douglass’s presentation as a self-made man.īlight’s alternative depiction of the event is as follows. He is a self-made hero who leaves a great deal unsaid, hidden from his readers and his biographers… it is as if he slips in and out of the room right when we so wish to know more – anything more about his private thoughts, motivations, and memories of conflicts within his personal life. ![]() In writing Douglass’s biography, Blight notes that all Douglass scholars are heavily reliant on these three autobiographies in which: His excitement for the Emancipation Proclamation, calling it “the greatest event of the century.” 2 However, there was a lot going on in Douglass’s personal life, which he hid from the public realm and omitted from his autobiographies. 1 During this period, Douglass spoke proudly and publicly of his childrens’ military service and Two of the Douglass children enlisted to fight for the Union, another left home for Mississippi to be a recruiter of black troops, and Frederick himself became a prominent leader in the war effort. In 1863, the Douglass family became increasingly involved with the Civil War. This paper will focus on a specific point in the novel where Blight highlights the experiences of Anna Douglass and Ottilie Assing, and will evaluate how his decision to include their experiences breaks down Douglass’s publicly projected image as a self-made man. Because of this unification, Blight is able to shed light on the experiences of these forgotten individuals and reassign their agency. However, Blight synthesizes the information in Douglass’s three autobiographies and merges these narratives with primary documents from Douglass’s peers and fellow historians’ work to produce an alternative narrative. ![]() The absence of information regarding Douglass’s private life in his three autobiographies, countless publications, and speeches, causes the impacts of many key actors within Douglass’s life, such as his wife, Anna, and rumored mistress, Ottilie Assing, to be forgotten. Two significant themes throughout Blight’s novel are the disparities between Douglass’s private and public life due to the lack of information he publicly disclosed about his personal affairs, and his public portrayal as a self-made man. Frederick Douglass : David Blight’s Frederick Douglass: Prophet of Freedom recounts the life of Frederick Douglass, a black American who escaped slavery to become one of the most prominent abolitionist figures in American History. ![]() ![]() ![]() Beers were savored, hard rock echoed off the mountains, and the idea for this collaboration between brewers and vintners ignited. Harpoon Brewery is thrilled to announce that its Big League New England IPA will now be widely available in Sweden. There we met renowned Italian brewer and music fanatic Moreno Ercolani. The gameplay mechanics and graphics are reminiscent of a free to play game, but without all the patron elements. The lower the number, the greater the availability, with a “BASE” availability meaning that the product is available in all or virtually all Systembolaget stores.Ĭrafted Exports is a premier international distributor of craft beers and spirits that specializes in using innovative, quality-control delivery processes to deliver the freshest products to markets across the world.The culmination of our week of visiting Italian breweries, sipping beers poolside, and toasting sunsets over the rolling hills of Tuscany was a stop at Birricio L’Olmaia in Montepulciano, Italy. Star Trek Legends is a turn based RPG with an epic storyline featuring all of your favorite Star Trek heroes and villains from every Star Trek canon. Big League Basqueland Brewing IPA - New England / Hazy Total () 608 Unique () 598 Monthly () 173 You 0 6.5 ABV No IBU (3. Then there are seven levels of availability in the chain of over 450 stores nationwide – T9, T7, T5, T3, T2, T1 and BASE. Some products are in the ‘ordering range’ or beställningssortimentet – orderable to stores, but not stocked. Within the Systembolaget there are several levels of availability. ![]() Systembolaget is the Swedish government-owned chain whose retail stores are the only ones in the country allowed to sell alcoholic beverages containing more than 3.5% alcohol, for take-home consumption. Following last Fall’s successful run of Flannel Friday, we know the Swedish craft beer drinkers are ready for Harpoon to become a big part of our thriving American Craft Beer market.”īig League will officially launch on June 1st. Harpoon takes their beloved hazy pale ale recipe and literally multiplies everything by two, including the tangerine, pineapple cake, and saltine tastes, the lime zest, orange, and mango aromas, and even the dry hops. Galatea and have been working with Harpoon through Crafted Exports for many years, bringing in special offerings for the On Trade, but this is our first win in the fixed assortment at the Swedish monopoly. The Harpoon Big League IPA admirably brings that much-needed concept into beer. As the brewers of New England’s Original IPA almost 30 years ago, we are thrilled to introduce our new big and juicy New England IPA with distinct notes of citrus, papaya, and ripe mango to Craft beer lovers across Sweden.”Ĭommenting on the release, Andrew Reed, Brand Manager at Galatea and, said: “We are so proud to announce the launch of Harpoon Big League in June at all Systembolaget stores. Bay Brewing Company: “We are honored to have Harpoon Big League selected to be carried by all Systembolaget stores throughout Sweden. Jon Schwartz, VP Business Development at Mass. League, Big League features the same tropical blend of hops and activity-minded ingredients like buckwheat kasha, chia seed, and sea salt, giving the IPA a tremendous amount of juicy hop character and a surprisingly refreshing finish. The Boston- and Vermont-based brewery won the coveted tender for system-wide availability with Systembolaget for the recently launched and highly anticipated IPA- the latest introduction to their League Family of beers that started in 2019 with a Hazy Pale Ale, Rec. ![]() – Harpoon Brewery is thrilled to announce that its Big League New England IPA will now be widely available in Sweden. ![]() ![]() At the Carlyle, Poindexter (vocals, harmonica) will be joined by Brian Koonin (guitar), Clifford Carter (piano), Richard Hammond (upright bass) and Ray Grappone (drums). Café Carlyle is located in The Carlyle, A Rosewood Hotel (35 East 76th Street, at Madison Avenue). Reservations made online at are $65 ($115 for premium seating) Tuesday–Thursday and $75 ($125 for premium seating) on Friday and Saturday. Reservations made by phone at 212.744.1600 are $70 ($120 for premium seating, $50 for bar seating) Tuesday–Thursday and $80 ($130 for premium seating, $65 for bar seating) on Friday and Saturday. David Johansen, the original punk hipster lounge lizard seems perfectly at home at the elegant Café Carlyle… with his exaggerated pompadour, crocodile grin, and raw Tom Waits growl, is 64 going on 14, and still having the time of his life.” Performances will take place Tuesday through Saturday. Stephen Holden of The New York Times praised his recent Café Carlyle performance: “That Buster Poindexter, a.k.a. As Poindexter, his previous engagements at the Café have been sellouts and he’s become one of the most revered artists to grace the Café, with TheaterMania calling his Café show “one of the most satisfying musical acts you’re likely to encounter in New York,” adding “this show is hot.” In what continues to become a Café tradition, the audience favorite returns to Café Carlyle for a two-week residency, February 10-21, including a special Valentine’s Day performance on February 14. ![]() Buster Poindexter, Johansen’s celebrated alter ego showcases his elegant crooning through R&B ballads. As a founding member of the New York Dolls and in a prolific solo career, David Johansen has been a seminal force in rock and roll, influencing countless singers and bands to this day. ![]() ![]() ![]() Download Free Forex MT4 Xmaster Formula Indicator Feel free to develop your own trading system based around it. Its performance will vary significantly depending on market conditions. Thus, this forex indicator provides false signals occasionally. Just like any other technical analysis tool, is not capable of providing accurate signals 100% of the time. Nonetheless, remember about having realistic expectations. A good forex indicator will most probably enhance your chance of success. ![]() The Xmaster Formula indicator is well worth adding to your trading collection. In the Navigator find the gauge name, right-click it and select Attach to the chart. Now go to the left side of your MT4 terminal. You can gain access to this folder by clicking the top menu options, which goes as follows:įile > Open Data Folder > MQL4 > Indicators (paste here). How to set up the Xmaster Formula indicator in MT4?ĭownload the Xmaster Formula.rar archive at the bottom of this post, unpack it, then copy and paste the Xmaster Formula.ex4 or Xmaster Formula.mq4 indicator files into the MQL4 folder of the Metatrader 4 trading platform. Avoid trading during unfavorable times and market conditions like low volume/volatility conditions, beyond major sessions, exotic currency pairs, wider spread, etc. It is crucial to know when to trade, but also when not to trade. To be a profitable trader you need to master discipline, emotions, and psychology. You can also use your own method of trade exitĪs always, to achieve good results, remember about proper money management. Take profit or exit trade when the Xmaster Formula turns green color or bullish trend arrow appears.Set stop loss above last swing high point.Open sell trade after both conditions are met.It should be followed by the downward arrow as bearish trend confirmation.The oscillator of Xmaster Formula turns red.You can also use your own method of trade exit Take profit or exit trade when the Xmaster Formula turns red color or bearish trend arrow appears.Set stop loss few pips below the last swing low point.Open buy trade after both conditions are met.It should be followed by the upward arrow as bullish trend confirmation.The oscillator of Xmaster Formula turns green. ![]() When the oscillator values are increasing, it means the trend is strengthening. The upward/downward arrows are plotted as confirmation signals for the market entries. The oscillator is made of a dotted line that takes green color when the trend is considered bullish or alternatively takes red color when the trend is considered bearish. The Xmaster Formula Forex Indicator consists of two elements: an oscillator and buy/sell arrows. How does it work? How to apply in trading? Feel free to experiment with the settings and parameters to fit your personal preferences. The default settings can be modified directly from the input tab. It is displayed in a separate window placed just below the main trading chart. The Xmaster Formula Indicator fits all kinds of timeframes and currency pairs. By some, this gauge is also called Xmaster Formula MT4 Indicator 2020, but in fact, it is one and the same tool. Both beginners and advanced forex traders will find the Xmaster Formula very useful and profitable when executed properly. One of the main advantages of the Xmaster Formula is its capability of demonstrating trend direction and the strength of that trend – all at the same time. Traders around the world appreciate the simplicity and accuracy of the provided trading signals. The Xmaster Formula Indicator is very popular trend-following forex indicator. Introduction to the Xmaster Formula MT4 Indicator 2020 ![]() ![]() ![]() We operated in a prolonged low-battery mode as we waited to return to our "normal" lives outside of lockdown. The people he and I were in those first four months of our relationship were like photocopies of photocopies. My partner's life as a musician pre-COVID involved a lot of late nights, big crowds, and airport lounge toasties.Īll of that vanished for him in March of 2020 and by the time he and I met he was working from home for the COVID hotline, waiting patiently for live music to return (which, we now know, would take a lot longer than initially anticipated). I'd spend all of my money, before arriving home with a story about how I'd driven a 50cc scooter down a Mexican freeway, and found myself soaked by a stream of urine released inexplicably from the back of a tour bus. I'd been properly single for two years, and would periodically disappear overseas for a few months. In a short paragraph, email us your pitch: more Love during a pandemicīefore the pandemic (AKA The Panny D™), I often described myself as having a very full life, which is to say I worked three jobs, had a wide circle of friends and read a lot of Elizabeth Gilbert. ![]() Chances are there's others facing the same highs, lows and life experiences. Now, almost a year has passed, and we're adjusting to the realities of who each of us is outside of our daily lockdown walks in search of Fitzroy's juiciest sandwich.Īs our lives unfurl to meet their former outlines, those of us who fell in love during lockdown are left wondering if our relationships would have progressed at the same rate, or even continued at all, had we not spent so much time together when we had absolutely nothing else to do.ĪBC Everyday's Perspectives is all about giving you a chance to share what you're going through. Two weeks later, we were locked down together for the better part of four months - or 103 days, to be exact. We drank orange wine and joked about ordering a whole fish as a snack and, at the end of the night, we shared a kiss against the bar's doorway (which, I'm sure was not at all annoying for the staff members who were just trying to close up). In May of 2021 (after Tiger King, but before the Delta wave) I went on a date with a musician who had the longest eyelashes I'd ever seen. ![]() ![]() ![]() This is revolutionary and will give rise to new organizations that reward all contributors with tokens, so everybody shares in the upside as the product/service gains in popularity. Shimmer a staging level sandbox has been launched by the IOTA Foundation in an effort to drive innovation on the blockchain. Bearish Bullish 10 Bearish 90 Iota (MIOTA) Price Prediction For Today, Tomorrow and Next 30 Days IOTA Prediction Table IOTA Historical According to the latest data gathered, the current price of IOTA is 0.17, and MIOTA is presently ranked No. ![]() A layer of trust can now be removed and people from around the globe who have never met in the physical world can work together towards a common goal. This new coordination mechanism is only possible through the advent of distributed ledger technologies. This framework includes digital tools to manage membership, governance, rewards, reputation, and the treasury for an organization that can run efficiently without legally binding nation-state contracts. What is a DAO and why are they so important? The best definition we’ve seen comes from Cooper Turley and that’s “an internet community with a shared bank account.” DAOs are a framework on which a new era of internet communities can be built. ![]() Some members of the IOTA Foundation have added “DAO” to their usernames, there’s a DAO Pioneers group that regularly meets, and we’ll soon have IOTA Community Treasury, Shimmer, and Assembly DAOs. You’ve probably been hearing a lot about Decentralized Autonomous Organizations (DAOs) lately. Risk Warning: Investing in digital currencies, stocks, shares and other securities, commodities, currencies and other derivative investment products (e.g. ![]() ![]() ![]() You can convert multiple columns from "string" to "date" format, which means "YYYYMMDD" format, by using the "pandas.to_datetime()" function. Change Multiple Columns from string Using pandas.to_datetime() ![]() Now, convert the datatype into datetime(‘yyyy-mm-dd’) format by using df = pd.to_datetime(df,format='%y%m%d') function.Ħ. You see that the Datatype of the "InsertedDate" column in the DataFrame is "object", that means, it is a string. Technologies = ,ĭf = pd.DataFrame(technologies,columns=) If You have a date in "yymmdd" format in the DataFrame column, and to change it from a string to a date (‘yyyy-mm-dd’) format. Use pandas.to_datetime() to change String to “yyyymmdd” Format Note that the dtype of InsertedDate column changed to datetime64 from object type.ĥ. This method is smart enough to change different formats of the String date column to date. Pandas.to_datetime() method is used to change String/Object time to date type (datetime64). Use pandas.to_datetime() to Change String to Date ![]() Our DataFrame contains column names Courses, Fee, Duration, Discount, and InsertedDate. Now, let’s create a DataFrame with a few rows and columns, execute these examples and validate results. # Use pandas.to_datetime() to convert string to "yyyymmdd" formatĭf = pd.to_datetime(df, format='%y%m%d') # Convert the data type of column 'Date' from string (YYYY/MM/DD) to datetime64ĭf = pd.to_datetime(df, format="%Y/%m/%d") # Use pandas.to_datetime() to convert string to datetime formatĭf = pd.to_datetime(df)ĭf = df.astype('datetime64') If you are in a hurry, below are some quick examples of how to change pandas DataFrame columns type from string to date format (date type datetime64. Quick Examples of Change String to Date in Pandas DataFrame ![]() |
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